Rasagiline (Azilect) for Parkinson's disease.
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چکیده
This Medicine Update is for people with Parkinson's disease who are taking, or thinking about taking, rasagiline. Independent, not-for-profit and evidence based, NPS enables better decisions about medicines and medical tests. We are funded by the Australian Government Department of Health and Ageing. Summary Rasagiline is a medicine that has recently been made available in Australia for the treatment of Parkinson's disease. Like other medicines for Parkinson's disease, rasagiline treats the symptoms but does not cure the condition. If you are just starting treatment, rasagiline may be prescribed on its own. In the later stages of Parkinson's disease, it may be prescribed in addition to levodopa. Although rasagiline is less eeective than levodopa at controlling the symptoms of Parkinson's disease, over a period of time the eeectiveness of levodopa wears oo. Also, you may develop unpredictable twisting, jerking and dancing movements (known as dyskinesia) as a side eeect of levodopa. Rasagiline can be added to levodopa therapy to extend the length of time that treatment is eeective, and reduce the amount of levodopa you need to take each day. When making a decision between rasagiline and other medicines, your doctor will consider how far your Parkinson's disease has advanced and the need to balance control of your symptoms with the potential side eeects of the diierent medicines.
منابع مشابه
Rasagiline in Parkinson's disease: a review based on meta-analysis of clinical data.
Rasagiline (Azilect(®)) is a selective and irreversible monoamine oxidase B inhibitor, which is well tolerated, safe, improves motor symptoms, and prevents motor complications in Parkinson's disease (PD). Rasagiline is effective in monotherapy and as an adjunct to levodopa-therapy, with beneficial effects on quality-of-life parameters in early and late stages of PD. In this review, we compare t...
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Parkinson's disease (PD) is a progressive neurodegenerative, dopamine deficiency disorder. The main therapeutic strategies for PD treatment relies on dopamine precursors (levodopa), inhibition of dopamine metabolism (monoamine oxidase [MAO] B and catechol-O-methyl transferase inhibitors), and dopamine receptor agonists. Recently, a novel selective and irreversible MAO B propargylamine inhibitor...
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عنوان ژورنال:
- The Medical letter on drugs and therapeutics
دوره 48 1249/1250 شماره
صفحات -
تاریخ انتشار 2006